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For most chromatographers poor sample reproducibility and mass transfer onto chromatographic column are generally the most critical issues in the method developement. Among others poor reproducibility and mass transfer can be caused by the degradation of the compounds by the glass inlet liner or by means of insufficient vaporization. Therefore selection of proper GC liner is very important and depends on the injection technique. Here you will find important information helping you with selectionof proper GC liner.
Issues surrounding the GC injector ports