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  5. Quantitation of PFAS in Water by LC-HR-QTOF MS/MS
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GCHPLCLiquid measurementMass spectrometryMetAmino KitSPE & MSPE

Quantitation of PFAS in Water by LC-HR-QTOF MS/MS

Per- and polyfluorinated alkyl substances (PFAS) are a diverse group of extensively used industrial chemicals. They are classified as persistent pollutants, with known environmental accumulation and global circulation. Due to their suspected toxicity, they are a growing threat to both humans and wildlife, and thus their analysis is an increasingly important task for analytical chemists. In this application a method of quantification of PFAS in water using a time-of-flight (QTOF) mass spectrometer is presented. In addition to the rapid, automated, and confident detection of expected and targeted PFAS compounds, analysis via this high resolution QTOF system offers the unique potential to detect unexpected or novel PFAS via retrospective reviewing of data sets. An unlimited number of compounds may be targeted in each run, and processing methods may be easily extended to include new PFAS compounds, providing flexibility for current and future regulatory criteria.