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Antidiabetic drugs (APK #564)

Diabetes is a chronic condition that occurs when the body cannot produce any or enough insulin, or cannot effectively use the insulin it produces. Type 2 diabetes has attained the status of a global pandemic. Sulfonylureas represent a class of medications used in the treatment of type 2 diabetes mellitus. All sulfonylureas contain a phenyl-sulfonyl-urea structure, which exerts the hypoglycemic effect. An efficient and reliable LC/MS method has been developed for сontrol of antidiabetic
medications of sulfonylurea class glibenclamide and glimepiride.